tag:blogger.com,1999:blog-354168122012-02-16T02:21:08.267-08:00MinC::Science Bork＊夢想。追尋。文字。生活。心情。隨寫。旅行。紀錄＊<br>A Za A Za Fighting !!<br>往成為「隨時都準備好的人」方向邁進...minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.comBlogger171100tag:blogger.com,1999:blog-35416812.post-28328656831814977272009-02-16T06:51:00.004-08:002009-02-16T07:05:10.543-08:00new therapy for HIV最近關於 HIV therapy 的新聞筆記[Nature] Stem-cell transplant wipes out HIV身患AIDS和血癌的病人，骨髓移植的時候選用帶有 CCR5 基因突變的捐贈者的骨髓，病患停藥後已有兩年沒再復發惡化(relapse)。歐洲人口有 1% 帶有 CCR5 的突變基因，這些人對 HIV 有抵抗力，因為 CCR5 是病毒進入細胞的 receptor，突變的 CCR5 可能讓 HIV 無法進入人體細胞而使人免於受病毒感染。市面上有 CCR5 inhibitor，是由 Pfizer 所製的 maraviroc，但需要和其他藥物一起使用。[BBC] HIV gene therapy trial promising這是 UCLA 發表在 Nautre Medicine 的研究報告，此基因治療已試用在74位病患身上，目前顯是為安全且能降低 HIV minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-46744103343506256282007-11-16T19:36:00.000-08:002007-11-16T19:43:20.394-08:00other misc resources> Science Journals> Cell Culture Handbook> Cell contamination> fluorochrome table> stable transfectionother notes:1000-1500 rpm for 5 mins....for freezing cellsTissue culture media contains Calcium and Magnesium ions, foetal calf serum contains proteins that are trypsin inhibitors. Both Mg2+/Ca2+ INHIBIT TRYPSIN. The reason why we use PBS without Ca2+/Mg2+ to wash the cells prior to minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com1tag:blogger.com,1999:blog-35416812.post-83723586576634329962007-11-02T15:11:00.000-07:002007-11-02T15:11:58.732-07:00[NEWS] C 型肝炎[BBC NEWS] How Hep C bypasses cell defences"The potentially-fatal hepatitis C virus evades the body's natural defences by slipping directly from cell to cell, scientists have found. This could mean treatments aimed at interrupting its progress won't work as well as hoped. University of Birmingham researchers told a Glasgow conference that this could explain the rapid spread of the virus in some minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-31570377289664403012007-11-01T17:37:00.000-07:002007-11-01T17:44:50.322-07:00[NEWS] 殺病毒，止癌症[SciAm] Kill the Virus, Stop the Cancer"Researchers have for the first time shown that as many as 1.3 million cases of cancer a year may one day be successfully treated or even prevented by targeting and destroying the viruses that cause them.Scientists at the Albert Einstein College of Medicine of Yeshiva University in New York City say the finding could pave the way for conquering human cancersminchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-45149600783028198452007-10-26T18:56:00.000-07:002007-10-26T19:04:05.556-07:00[NEWS] Setback for Nigeria's Polio Fighters[TIME] Setback for Nigeria's Polio Fighters"Health workers in Nigeria fear they're on the verge again — of collapse. When the World Health Organization and the Centers for Disease Control revealed in early October that 69 Nigerian children had been paralyzed by polio virus since 2005 — and had contracted the illness through exposure to the live virus found in the oral vaccine drop — it was the minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-88385742509509372822007-10-26T18:39:00.000-07:002007-10-26T18:41:56.820-07:00[NEWS] Study to probe whether acne drug can slow MS[CTV.ca] Study to probe whether acne drug can slow MS"Researchers in Calgary are preparing to begin a new study to see whether a commonly available acne medication could help delay the crippling effects of multiple sclerosis.The medication, called minocycline, has been available for over 30 years. If it's proven effective in delaying the progress of MS, it could offer an inexpensive option for minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com1tag:blogger.com,1999:blog-35416812.post-72936630100280510192007-10-18T07:09:00.000-07:002007-10-18T07:13:45.956-07:00好用線上資源online nucleotide concentration convertor1. ng/ml to pM (vice visa): http://www.ambion.com/techlib/append/concentration_calculator.html2. weight to mole (vice visa): http://molbiol.edu.ru/eng/scripts/h01_07.html (很多單位大小可選)minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-56364078099064145512007-10-11T17:54:00.001-07:002007-10-11T18:03:52.829-07:00[NEWS] HPV Vaccine原來HPV Vaccine 用的只有viral proteins，而不是viral DNA，所以專家 Dr. Murphy 說她很安全，更多資訊在：[CBC] Your Interview: HPV VaccineDr. Murphy 是加拿大多倫多大學(Univ. of Toronto)的教授。minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-36391386977506202472007-10-11T16:32:00.000-07:002007-10-11T18:04:51.664-07:00[NEWS] Nobel Prize 2007今年的諾貝獎嗎？什麼時候出來的？A Knockout Award in Medicine去年是RNAi knockdown，今年換knockout mice。minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-37290965843884138342007-10-11T16:25:00.000-07:002007-10-11T18:09:18.138-07:00[NEWS] HIV Vaccine愛滋疫苗上個月公佈失敗的新聞。從PubMed 的連結點進去會看到這則新聞公告：Clinical Alter: Immunizations are discontinued in two HIV Vaccine trials其他相關新聞：Clinical Alter: Immunizations are discontinued in two HIV Vaccine trials[NIAID] Q&A: HVTN 502 and HVTN 503 HIV Vaccine Clinical Tirals[SciAm] HIV Vaccine Hopeful Fails[Science] Building an HIV-Proof Immune System[Science] AIDS Research: Promising Prevention Interventions Perform minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-1165477499212395212006-12-06T23:44:00.000-08:002007-02-03T17:29:49.545-08:00[隨畫] 星空這是我很久以前畫的，一直擱著。昨天在他踢的網誌看到他的繪畫教學，不禁想要試試看。之前是用原子筆畫在類似牛皮紙的紙上，今天用粗黑筆在白紙上用重畫了一次再掃描進電腦，然後試著用PhotoShop改圖加上色，就成了下面的樣子，看起來效果還不賴。minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-1165477461982504982006-12-06T23:43:00.001-08:002007-02-03T17:30:18.628-08:00[隨畫] 孤單忍不住又試畫了一張。突然很想買一本 PhotoShop 的教學書來看，嗯…先去圖書館看看有沒有好了。minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-1165477420454200762006-12-06T23:43:00.000-08:002007-02-03T17:30:46.236-08:00[隨畫] 未來五年前所看到的未來...五年後好像還是一樣...希望在未來的一年內，可以完成三分之一。minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-1165477383404484892006-12-06T23:42:00.001-08:002007-02-03T17:31:03.946-08:00[塗鴉] 雲忘了畫這篇時的心情是什麼了...只知道，現在還是不知道抓到雲是什麼樣的感覺。minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-1165477341993361192006-12-06T23:42:00.000-08:002007-02-03T17:33:08.715-08:00[隨畫] 追尋一樣是以前畫的圖...加油加油，不要灰心喔～minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-1165477289115130642006-12-06T23:40:00.000-08:002007-02-03T17:32:48.588-08:00[隨畫] 路因為....所以... 沒有路的話，就自己走出一條路來吧！minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0tag:blogger.com,1999:blog-35416812.post-1165477089865247392006-12-06T23:36:00.000-08:002007-02-03T17:31:31.802-08:00[隨畫] 破釜沉舟凡事不能太龜毛...過河拆橋 破釜沉舟 傻傻分不清楚PS. 破「ㄈㄨˇ」沉舟的「ㄈㄨˇ」是這個「釜」，不是這個「斧」喔！minchttp://www.blogger.com/profile/06977448701991210150noreply@blogger.com0